Autopsy report · NCT05237284

Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS)

“The study was terminated as its Part A did not meet the primary endpoint.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 1 year 11 months before it stopped.
• 305 participants enrolled.
• Results were posted on the registry 1 year after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Sanofi

Sponsor type

Industry

Conditions

Amyotrophic Lateral Sclerosis

Interventions

SAR443820; Placebo

Participants

305

Sites

63

Countries

Belgium, Canada, China, France, Germany, Italy, Japan, Netherlands, Poland, Spain, Sweden, United Kingdom and more

Trials that died the same way

• Study of Copanlisib in Combination With Standard Immunochemotherapy in Relapsed Indolent Non-Hodgkin's Lymphoma (iNHL)
  “Company decided to terminate this study due to study did not meet the primary endpoint.” (90% match in meaning)
• A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care Treatments
  “The study did not meet the primary endpoint.” (85% match in meaning)
• Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone in Patients Renal Cell Carcinoma
  “The study did not meet endpoint.” (83% match in meaning)
• Integrative Liver-Targeted Therapy for Diabetic Macular Edema: Using "Tauroursodeoxycholate" or Traditional Chinese Medicine.
  “The study was terminated due to additional regulatory requirements that could not be completed within the established academic timeline. As a result, continuation of the study was not feasible.” (81% match in meaning)
• The Role of Splinting in Fingertip Injuries
  “Very few subjects were enrolled. Therefore, the study was terminated.” (80% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.