Autopsy report · NCT04601857

Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma

“Sponsor decided to discontinue the study due to strategic considerations and not due to any safety-related concerns.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 4 years 8 months before it stopped.
• 43 participants enrolled.
• Results were posted on the registry 3 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Taiho Oncology, Inc.

Sponsor type

Industry

Conditions

Advanced and Metastatic Urothelial Cancer

Interventions

Futibatinib; Pembrolizumab

Participants

43

Sites

18

Countries

France, Spain, United States

Trials that died the same way

• A Study of ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation
  “The Sponsor terminated the study due to futility. The decision to stop the study was not based on safety concerns.” (87% match in meaning)
• A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome
  “The study was terminated by Sponsor and the decision was not due to any safety or efficacy reasons.” (85% match in meaning)
• Efficacy and Safety of Teriflunomide in Patients With Relapsing Multiple Sclerosis and Treated With Interferon-beta
  “Sponsor decision to prematurely stop the study, not linked to any safety concern.” (84% match in meaning)
• Study of Obeldesivir to Treat Children With Respiratory Syncytial Virus (RSV) Infection
  “Study was terminated by Sponsor; the decision was not due to any safety findings.” (84% match in meaning)
• Colorectal Lesion Evaluation and Appropriate Resolution (CLEAR) Study
  “Study terminated per sponsor decision due to operational reasons. The termination was not a result of any participant safety concerns.” (82% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.