Autopsy report · NCT04335786

Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease

“Enrollment was stopped to facilitate successful enrollment for the ACE2RAS-domain of the REMAP-CAP trial.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year 1 month before it stopped.
• 23 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Radboud University Medical Center

Sponsor type

University, hospital or other

Conditions

Acute Respiratory Distress Syndrome; SARS-CoV-2; COVID; COVID-19; Severe Acute Respiratory Syndrome

Interventions

Valsartan (Diovan); Placebo oral tablet

Participants

23

Sites

7

Countries

Netherlands

Trials that died the same way

• An Extension of Protocol PRO 140_CD01 Study
  “FDA required the sponsor to halt enrollment in the trial and transition participants to available therapies for the treatment of their disease. The trial was subsequently terminated once participants were transitioned.” (64% match in meaning)
• The Role of Osteopathic Manipulative Medicine in Recovery From Concussions
  “Due to lower than anticipated enrollment number, this study was stopped.” (64% match in meaning)
• Imatinib Mesylate and Gemcitabine in Treating Patients With Locally Advanced, Metastatic, or Recurrent Pancreatic Cancer
  “Closed to accrual to allow enrollment on another more promising trial.” (64% match in meaning)
• Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias
  “Clinical trial was halted prematurely due to low enrollment” (64% match in meaning)
• Revlite Laser System Compared to the Candela Alex TriVantage System Refractory Mixed Type Melasma
  “The study stopped because patient enrollment requirements were not met.” (62% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.