Autopsy report · NCT04217304

SONOthrombolysis in Patients With an ST-segment Elevation Myocardial Infarction With fibrinoLYSIS (SONOSTEMI-LYSIS) Trial

“Unlikely to demonstrate the intended benefit within the planned study design and statistical framework.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 year 2 months before it started.
• Ran for about 4 years 11 months before it stopped.
• 41 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

University of Alberta

Sponsor type

University, hospital or other

Conditions

ST Elevation Myocardial Infarction

Interventions

Definity® with High Mechanical Index Ultrasound

Participants

41

Sites

1

Countries

Canada

Trials that died the same way

• A Coach-Guided Online Acceptance and Commitment Therapy (ACT) Intervention for Stroke Survivors
  “The research team decided not to implement this study.” (63% match in meaning)
• Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess
  “The study team decided not to pursue this study.” (63% match in meaning)
• SOM230 Ectopic ACTH-producing Tumors
  “Due to stringent inclusion/exclusion criteria, study investigator deemed it not feasible.” (61% match in meaning)
• Physical Exercise for Augmenting Cognitive Health (PEACH)
  “The study protocol was not feasible. We made several modifications but halted the study prematurely before we met our target sample size goal.” (61% match in meaning)
• A Study to Investigate the Efficacy and Safety of Balovaptan (RO5285119) in Participants With Autism Spectrum Disorder (ASD)
  “The 24-week analysis indicated no clinical or statistical benefit for the primary endpoint for the overall study population. No new safety concerns identified.” (60% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.