Autopsy report · NCT02901431
A Study to Investigate the Efficacy and Safety of Balovaptan (RO5285119) in Participants With Autism Spectrum Disorder (ASD)
Cause of deathFutility
“The 24-week analysis indicated no clinical or statistical benefit for the primary endpoint for the overall study population. No new safety concerns identified.”
Life of this trial
- Registered 2 months before it started.
- Ran for about 3 years 7 months before it stopped.
- 339 participants enrolled.
- Results were posted on the registry 7 months after it ended.
Vital statistics
- Status
- Terminated
- Phase
- Phase 2
- Sponsor
- Hoffmann-La Roche
- Sponsor type
- Industry
- Conditions
- Autism Spectrum Disorder
- Interventions
- Placebo; RO5285119
- Participants
- 339
- Sites
- 45
- Countries
- United States
Trials that died the same way
- A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients
“The study was terminated on August 6, 2012, because 2 large Phase 3 studies showed no clinical benefit. This decision was not based on any new safety concerns.” - Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)
“Lack of Efficacy, no safety concern.” - Safety and Efficacy of Niclosamide in Patients With COVID-19 With Gastrointestinal Infection
“The termination of the study was a decision based on topline data analysis (no efficacy as per Day 43) of the study data.” - A Pilot Study of Candesartan as a Treatment for Cocaine Dependence
“Results of interim efficacy analysis showed results were not promising.” - An Efficacy and Safety Study of JNJ-26113100 in the Treatment of Adult Atopic Dermatitis
“The study was stopped due to a non-clinical safety finding.”
Look deeper
- The official registry record (the source of truth)
- Record history: every change the sponsor made
- Open it in the database
Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.