Autopsy report · NCT03946774

Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling

“Temporarily paused due to COVID-19 and expected to resume. This is not a suspension of IRB approval. PI has left the institution.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 7 months before it started.
• Ran for about 3 years 7 months before it stopped.
• 21 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Washington University School of Medicine

Sponsor type

University, hospital or other

Conditions

Dietary Protein

Interventions

Dietary protein shake

Participants

21

Sites

1

Countries

United States

Trials that died the same way

• Bortezomib in Combination With Ibrutinib in Ibrutinib Relapsed Mantle Cell Lymphoma
  “Enrollment and/or interactions/interventions temporarily paused due to COVID-19 and expected to resume in the future. This is not a suspension of IRB approval.” (89% match in meaning)
• Evaluation of a Computerized Intervention for Learning to Re-Evaluate Suicidal Thoughts
  “Face-to-face appointments, which were required by the IRB for suicide risk evaluation, were suspended by the IRB during the COVID-19 pandemic. During this pause, the PI left the institution. Thus, all study activities were terminated.” (73% match in meaning)
• Exhaled Breath Condensate pH in Patients With Cough Caused by Gastroesophageal Reflux
  “IRB approval not renewed/approval lapsed. Prior status: insufficient enrollment; study suspended pending analysis” (72% match in meaning)
• Clinical Data Collection for Obstetric Ultrasound Algorithms
  “Study paused temporarily pending IRB approval of an amendment to the protocol and consent form.” (72% match in meaning)
• The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients
  “Permanently terminated due to COVID-19 given the poor vaccine penetrance in liver transplant recipients. This is not a suspension of IRB approval.” (72% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.