Autopsy report · NCT03907202

A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM

“The trial was planned to be conducted in 4 cohorts but was terminated after completion of Cohort 2 for strategic reasons due to limited PD effects.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year 8 months before it stopped.
• 25 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

KeyBioscience AG

Sponsor type

Industry

Conditions

Type II Diabetes Mellitus

Interventions

Daily injection of KBP/placebo for up to 28 days

Participants

25

Sites

1

Countries

Germany

Trials that died the same way

• Stop Exogenous Allergic Alveolitis (EAA) in Childhood
  “After several years of recruitment only 4 patients were included. Study timelines for study completition too long. Decided to terminate trial.” (77% match in meaning)
• A Study of De-immunized DI-Leu16-IL2 Administered Subcutaneously in Participants With B-cell NHL
  “Clinical benefit was noted in the earlier portion of the trial; hence, participants were not enrolled in 2 expansion cohorts and the study was terminated early.” (75% match in meaning)
• Phase II Study of TAEST16001 in Soft Tissue Sarcoma
  “The study was terminated due to initiation of a new clinical trial with an updated study design.” (75% match in meaning)
• Endoscopic Full Thickness Resection of Gastric Subepithelial Tumors (FROST)
  “According to study protocol the trial was terminated because the recruitment of trial participants was insufficient.” (73% match in meaning)
• Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer
  “The clinical trial has been terminated due to the revocation of funding. Although one subject was enrolled, the participant withdrew prior to receiving any treatment. No trial-related procedures generating evaluable clinical data were performed.” (72% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.