Autopsy report · NCT03846466

Study of KHK 4323 in Healthy Volunteers and Subjects With Atopic Dermatitis

“The study terminated for safety reasons.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 10 months before it stopped.
• 5 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

Kyowa Kirin Co., Ltd.

Sponsor type

Industry

Conditions

Atopic Dermatitis

Interventions

KHK4323 IV/S; KHK4323 SC/S; KHK4323 IV/M; Placebo IV/S; Placebo IV/M; Placebo SC/S

Participants

5

Sites

1

Countries

Japan

Trials that died the same way

• Satavaptan for the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver
  “Study was terminated due to safety reason.” (94% match in meaning)
• Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI)
  “The study was terminated due to administrative, non-safety related reasons.” (90% match in meaning)
• Efficacy and Safety of Clevudine Compared With Adefovir in Patients With HBeAg Positive Chronic Hepatitis Due to Hepatitis B Virus
  “The study was terminated in the interest of patient safety.” (88% match in meaning)
• Randomized Controlled Study to Incentivize Doctors for Appropriate Use of Medical Care in NL
  “The study was terminated due to logistical reasons” (87% match in meaning)
• An Evaluation Of PF-03715455 In Moderate To Severe Uncontrolled Asthma
  “The termination was due to business reasons. No safety or efficacy concerns contributed to the termination of the study” (87% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.