Atopic Dermatitis

Why trials studying Atopic Dermatitis stopped, in this sample of ClinicalTrials.gov.

19 stopped trials with a clear reason; 53% ended for non-scientific reasons.

Trials

• Topical ENS-002 for Atopic Dermatitis in Adults
  NCT06469385 · TERMINATED · safety
  “Planned safety, efficacy and proof of mechanism obtained”
• CBP-201 in Adolescent and Adult Patients With Moderate-to-severe Atopic Dermatitis
  NCT05614817 · WITHDRAWN · funding business
  “Sponsor Decision”
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis
  NCT05387707 · TERMINATED · futility
  “In Part A of the study, oral difelikefalin as adjunct to topical corticosteroids (TCS) did not demonstrate meaningful clinical benefit compared to TCS alone.”
• An Efficacy and Safety Study of RPT193 in Adults With Atopic Dermatitis
  NCT05399368 · TERMINATED · regulatory
  “Study on clinical hold by FDA”
• Immunomodulation by OM-85 (Broncho-Vaxom) in Early AD
  NCT05222516 · TERMINATED · futility
  “Recommendation of DSMB (futility of Endpoints)”
• Study the Safety and Efficacy of DBI-001 Gel Versus Aqueous Gel
  NCT05253755 · TERMINATED · funding business
  “Sponsor suspension and not due to safety or site-related matters.”
• BROadband vs Narrowband photoTherapy for Eczema Trial Nested in the CACTI Cohort
  NCT04818138 · TERMINATED · funding business
  “End of funding period.”
• Study of KHK 4323 in Healthy Volunteers and Subjects With Atopic Dermatitis
  NCT03846466 · TERMINATED · safety
  “The study terminated for safety reasons.”
• The Role of Bathing Additives in the Treatment of Pediatric Atopic Dermatitis
  NCT03775590 · TERMINATED · slow accrual
  “Study closed due to lack of enrollment.”
• A Study of LY3375880 in Adults With Moderate-to-Severe Atopic Dermatitis
  NCT03831191 · TERMINATED · futility
  “The study was terminated for lack of efficacy after an interim analysis was performed”
• Efficacy, Safety, and Pharmacokinetic Profiles of REGN3500 Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis
  NCT03738423 · TERMINATED · futility
  “Lack of efficacy”
• Efficacy and Safety of REGN3500 Monotherapy and Combination of REGN3500 Plus Dupilumab in Adult Patients With Moderate-to-Severe Atopic Dermatitis
  NCT03736967 · TERMINATED · futility
  “Lack of efficacy”
• A Study to Assess Efficacy, Safety, Tolerability and Pharmacokinetics (PK)/Pharmacodynamics (PD) of MOR106 in Subjects With Moderate to Severe Atopic Dermatitis
  NCT03568071 · TERMINATED · futility
  “MOR106 clinical development in atopic dermatitis was stopped for futility”
• Can Vitamin D Treatment Help Treat Moderate to Severe Atopic Dermatitis in Young Children? the D-Vex Pilot Study
  NCT03257215 · TERMINATED · slow accrual
  “Recruitment very slow \& ongoing funding not obtained.”
• A Study of Intravenous MK-8226 in Participants With Moderate-to-Severe Atopic Dermatitis (MK-8226-003)
  NCT01732510 · TERMINATED · funding business
  “The study was prematurely stopped due to business reasons.”
• Management of Eczema by Specific Probiotic Strains
  NCT01230190 · WITHDRAWN · safety
  “Because of safety issues/support concerning the multispecies probiotic mixture”
• Vitamin D Deficiency and Atopic Dermatitis
  NCT01337635 · TERMINATED · slow accrual
  “Not meeting enrollment goals.”
• Tolerance and Efficacy of Formulation 609580 20 Versus Formulation 609209 in Children With Atopic Dermatitis
  NCT00931411 · TERMINATED · slow accrual
  “Patients would improve naturally due to weather conditions”
• A Pediatric Longitudinal Evaluation to Assess the Long-Term Safety of Protopic for the Treatment of Atopic Dermatitis
  NCT00475605 · TERMINATED · funding business
  “Terminated early, endorsed by the FDA based on futility of continuation.”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.