Autopsy report · NCT03799445

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

“\<75% participation”

The sponsor’s own words in the registry.

Life of this trial

• Registered 7 months before it started.
• Ran for about 6 years 9 months before it stopped.
• 37 participants enrolled.
• Results were posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

M.D. Anderson Cancer Center

Sponsor type

University, hospital or other

Conditions

Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma; Oropharyngeal Basaloid Carcinoma; Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Interventions

Intensity-Modulated Radiation Therapy; Ipilimumab; Nivolumab; Quality-of-Life Assessment; Questionnaire Administration

Participants

37

Sites

1

Countries

United States

Trials that died the same way

• ONC201 in Treating Patients With Relapsed or Refractory Acute Leukemia or High-Risk Myelodysplastic Syndrome
  “\<75% participants” (87% match in meaning)
• Vapocoolant Analgesia for Breast Lymphoscintigraphy
  “\<75% accrued participants” (76% match in meaning)
• Supplementation With Polyphenol-Rich Foods and Atrial Fibrillation After a Cardiac Surgery
  “low participation rate” (72% match in meaning)
• Physiotherapy and Therapeutic Education After Total Knee Arthroplasty.
  “low participation” (70% match in meaning)
• Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line Chemotherapy
  “Lack of participations (8 of 25)” (64% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.