Autopsy report · NCT03630224

Plasmalyte Versus Saline in Trauma Patients

“Premature termination due to futility following interim analysis”

The sponsor’s own words in the registry.

Life of this trial

• Registered 10 months before it started.
• Ran for about 4 years 2 months before it stopped.
• 365 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Assistance Publique - Hôpitaux de Paris

Sponsor type

University, hospital or other

Conditions

Severe Trauma Patients; Acute Kidney Injury

Interventions

Plasmalyte Viaflo; NaCl 0.9%

Participants

365

Sites

1

Countries

France

Trials that died the same way

• Efficacy Study of Dasatinib in Locally Advanced Triple-Negative Breast Cancer Patients
  “terminated due to futility after interim analysis” (87% match in meaning)
• Mortality Due to Malignancy in Patients With Idiopathic Venous Thromboembolism
  “Terminated because of futility to continue, after planned interim analysis.” (80% match in meaning)
• Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of Infection
  “termination due to futility (very slow patient enrollment)” (75% match in meaning)
• The MONOVISC Hip Osteoarthritis Study
  “The results of the interim analysis indicate the futility criterion have been met, therefore enrollment was terminated.” (75% match in meaning)
• Hypothermia After In-hospital Cardiac Arrest
  “interim analysis with stopping for futility” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.