Autopsy report · NCT03580772

Persona MC vs Attune Total Knee Replacement Study

“Due to ongoing issues with recruitment, it was decided it was best to terminate the study and focus resources on other priorities.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 6 months before it started.
• Ran for about 3 years 5 months before it stopped.
• 31 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Sponsor

University of Leeds

Sponsor type

University, hospital or other

Conditions

Knee Osteoarthritis

Interventions

Persona TKR; Attune TKR

Participants

31

Sites

1

Countries

United Kingdom

Trials that died the same way

• Study of Vascular Function Before vs After Smoking an E-cigarette as Compared to a Normal Cigarette
  “due to recruitment reasons the study was prematurely ended” (74% match in meaning)
• Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome
  “The study was terminated due to recruitment challenges” (73% match in meaning)
• Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery
  “The study was terminated due to a considerably lower recruitment rate than anticipated” (73% match in meaning)
• Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss
  “The study was terminated following a strategic decision to halt recruitment due to persistently slow enrollment. This decision was not driven by any new or unexpected safety concerns.” (73% match in meaning)
• A Safety Study of PF-08046045/SGN-35T in Adults With Advanced Cancers
  “Study terminated as part of strategic considerations” (73% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.