Autopsy report · NCT02187809

Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

“The study was terminated due to recruitment challenges”

The sponsor’s own words in the registry.

Life of this trial

• Registered 8 months before it started.
• Ran for about 7 months before it stopped.
• 3 participants enrolled.
• Results were posted on the registry 1 year 4 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

H. Lundbeck A/S

Sponsor type

Industry

Conditions

Dravet Syndrome

Interventions

Clobazam

Participants

3

Sites

9

Countries

Mexico, United States

Trials that died the same way

• Early Versus Late Amniotomy Following EAB Cervical Ripening
  “Study was terminated due to difficulties in recruitment” (94% match in meaning)
• Research Study of Greater Occipital Nerve Block As A Treatment For Prolonged Migraine Attacks
  “Study terminated due to inadequate recruitment” (90% match in meaning)
• Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery
  “The study was terminated due to a considerably lower recruitment rate than anticipated” (90% match in meaning)
• Alfuzosin Versus Placebo in Acute Urinary Retention
  “The study was early terminated due to slow and difficult recruitment” (89% match in meaning)
• ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers (SURPASS-2)
  “Study was terminated due to difficulty recruiting subjects and lack of efficacy” (89% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.