Autopsy report · NCT03567291

Evaluation of Safety and Tolerability of Long-term TEV-50717 (Deutetrabenazine) for Treatment of Tourette Syndrome in Children and Adolescents

“The parent trials did not meet the primary endpoints of reduction in motor and phonic tics.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 2 years before it stopped.
• 228 participants enrolled.
• Results were posted on the registry 10 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Teva Branded Pharmaceutical Products R&D, Inc.

Sponsor type

Industry

Conditions

Tourette Syndrome

Interventions

TEV-50717; Placebo

Participants

228

Sites

76

Countries

Argentina, Australia, Canada, Colombia, Denmark, Hungary, Italy, Mexico, Poland, Russia, Serbia, South Korea and more

Trials that died the same way

• Venetoclax and Quizartinib in Treating Patients With FLT3-mutated Recurrent or Refractory Acute Myeloid Leukemia
  “This study was terminated early due to other competing trials, therefore did not go on to the Phase II portion of the study.” (65% match in meaning)
• A Study of Ustekinumab in Participants With Active Polymyositis and Dermatomyositis Who Have Not Adequately Responded to One or More Standard-of-care Treatments
  “The study did not meet the primary endpoint.” (63% match in meaning)
• OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD)
  “The primary endpoint was not achieved in the study.” (62% match in meaning)
• An Efficacy and Safety Study of Lanabecestat (LY3314814) in Early Alzheimer's Disease
  “An independent assessment concluded the trial was not likely to meet the primary endpoint upon completion and therefore, trial stopped for futility” (60% match in meaning)
• Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone in Patients Renal Cell Carcinoma
  “The study did not meet endpoint.” (60% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.