Autopsy report · NCT03548064

A Double-Blind Placebo-Control Dose Escalating Study to Evaluate the Safety and Immunogenicity of dmLT by Oral, Sublingual and Intradermal Vaccination in Adults Residing in an Endemic Area

“COVID 19 cases at the site”

The sponsor’s own words in the registry.

Life of this trial

• Registered 10 months before it started.
• Ran for about 1 year 10 months before it stopped.
• 75 participants enrolled.
• Results were posted on the registry 1 year 1 month after it ended.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

National Institute of Allergy and Infectious Diseases (NIAID)

Sponsor type

US National Institutes of Health

Conditions

Gastroenteritis Escherichia Coli; Immunisation

Interventions

Placebo; Placebo; Placebo; Recombinant Double Mutant Heat-Labile Toxin LT(R192G/L211A) (dmLT) Oral enterotoxigenic Escherichia coli (ETEC) Vaccine; Recombinant Double Mutant Heat-Labile Toxin LT(R192G/L211A) (dmLT) Oral enterotoxigenic Escherichia coli (ETEC) Vaccine; Recombinant Double Mutant Heat-Labile Toxin LT(R192G/L211A) (dmLT) Oral enterotoxigenic Escherichia coli (ETEC) Vaccine

Participants

75

Sites

2

Countries

Bangladesh, United States

Trials that died the same way

• Ivermectin in Adults With Severe COVID-19.
  “Lack of severe COVID-19 cases in the place of study” (76% match in meaning)
• Vitamin C to Reduce Vasopressor Dose in Septic Shock
  “COVID 19” (75% match in meaning)
• Efficacy of a Transcranial Vibrating System for Mitigation of Migraine Associated Vertigo
  “COVID-19 general concerns.” (72% match in meaning)
• Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement
  “The Outbreak of COVID-19.” (72% match in meaning)
• A Personalized Prehabilitation Intervention In Elective Joint Replacement Surgery
  “Covid-19 Crisis” (71% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.