Autopsy report · NCT03489577

The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients

“Interim analysis provided enough data”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 years 9 months after it had already started.
• Ran for about 2 years before it stopped.
• 15 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Sponsor

UMC Utrecht

Sponsor type

University, hospital or other

Conditions

Multiple Trauma; Sepsis; Innate Immune Response; Disorder of Neutrophils; Multiple Organ Dysfunction Syndrome

Participants

15

Sites

1

Countries

Netherlands

Trials that died the same way

• Epcoritamab and Tazemetostat for the Treatment of Relapsed or Refractory Grade I-IIIa Follicular Lymphoma
  “Pending Interim Analysis” (80% match in meaning)
• ICVT in HPV-induced Genital Lesions of Immunocompromised and Immunocompetent Patients
  “Lack of effect in interim analysis” (79% match in meaning)
• Efficacy Study of Polyunsaturated Fatty Acids in Children and Adolescents With Attention Deficit/ Hyperactivity Disorder
  “The sample size of the planned interims analysis was achieved” (76% match in meaning)
• Liberty Analyzer WBC System: Reference Interval Study
  “For interim analysis.” (76% match in meaning)
• A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)
  “Upon interim analysis, sufficient data was accrued to assess study hypotheses.” (70% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.