Autopsy report · NCT03488225

Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia

“the study was closed early due to competing trials”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 2 years before it stopped.
• 4 participants enrolled.
• Results were posted on the registry 1 year after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

M.D. Anderson Cancer Center

Sponsor type

University, hospital or other

Conditions

Acute Lymphoblastic Leukemia in Remission; B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

Interventions

Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin Hydrochloride; Inotuzumab Ozogamicin; Laboratory Biomarker Analysis

Participants

4

Sites

1

Countries

United States

Trials that died the same way

• Tolfenamic Acid, Gemcitabine and Radiation for Locally Advanced or Metastatic Pancreatic Cancer Requiring Radiation
  “The study closed prior to enrolling any participants.” (76% match in meaning)
• A Study of Alectinib in RET-rearranged Non-small Cell Lung Cancer or RET-mutated Thyroid Cancer
  “Study closed due to slow accrual and lack of efficacy.” (75% match in meaning)
• Immunotherapies in Combination With Stereotactic Body Radiation Radiotherapy in Microsatellite Stable (MSS) Metastatic Colorectal Cancer (mCRC)
  “The trial is closing due to findings from a related study, prompting the sponsor to discontinue development and end this study.” (74% match in meaning)
• Sunitinib in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer Who Have Tumor Cells in the Bone Marrow
  “Closed prematurely due to emerging data on toxicity and competing trials.” (74% match in meaning)
• Trial of High Dose Melphalan/Stem Cell Transplant With or Without Bortezomib
  “Enrollment held for toxicity evaluation; then closed due to competing trial” (72% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.