Autopsy report · NCT03362294

Safety and Efficacy of Monthly Long-acting IM Injection of 25mg or 40 mg GA Depot in Subjects With PPMS

“The study was terminated early as part of a global realignment of Sponsor's clinical development programs. This decision is not related to any safety concerns regarding the IP.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 7 years 6 months before it stopped.
• 30 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Mapi Pharma Ltd.

Sponsor type

Industry

Conditions

Primary Progressive Multiple Sclerosis

Interventions

GA Depot 40mg once monthly; GA Depot 25mg once monthly

Participants

30

Sites

7

Countries

Israel, Moldova

Trials that died the same way

• A Study of GFH312 in Patients With Peripheral Artery Disease (PAD) and Intermittent Claudication (IC)
  “The study was terminated by sponsor for reasons of adjusted clinical development strategy.” (81% match in meaning)
• Study of CX1106 in Patients With Advanced Head and Neck Squamous Cell Carcinoma
  “The study was terminated voluntarily by the sponsor due to changes in clinical development strategy.” (81% match in meaning)
• An Evaluation of the Erchonia Laser As a Non-Invasive Treatment to Improve the Appearance of Skin Laxity
  “The study was terminated early due to sponsor decision unrelated to safety or efficacy findings” (80% match in meaning)
• Study of Ataluren (PTC124) in Hemophilia A and B
  “Study was terminated early due to Sponsor decision and not reflective of adverse safety findings.” (79% match in meaning)
• A Study to Assess Recurrence of Actinic Keratosis in Participants Treated With Methyl Aminolevulinate Hydrochloride Cream or Vehicle Cream Who Achieved Complete Response to Treated Lesions in Earlier Study
  “The study was terminated early as per Sponsor's decision” (79% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.