Autopsy report · NCT03150004

Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

“No longer have funding support to complete the pharmacogenetics component.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 7 years 9 months before it stopped.
• 53 participants enrolled.
• Results were posted on the registry 1 year 1 month after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Medical College of Wisconsin

Sponsor type

University, hospital or other

Conditions

Acute Myeloid Leukemia; Myelodysplastic Syndrome

Interventions

Cladribine, Cytarabine, Mitoxantrone, G-CSF (CLAG-M) regimen; Cladribine and Cytarabine (CLLDAC) Regimen

Participants

53

Sites

1

Countries

United States

Trials that died the same way

• Muscle, Essential Amino Acids, and eXercise in Heart Failure
  “There is no longer any funding to support the study” (73% match in meaning)
• CPI-613 (Devimistat) in Combination With Chemoradiation in Patients With Pancreatic Adenocarcinoma
  “The pharmaceutical funder pulled funding and no longer plans to develop the drug further.” (73% match in meaning)
• Study of Access Site for Enhancing PCI in STEMI for Seniors (SAFE STEMI for Seniors)
  “Funding for this study has been discontinued.” (69% match in meaning)
• ARTerial EMbolization for haemorrhoIdal Disease (ART.EM.I. Study)
  “Funding no longer available.” (67% match in meaning)
• Oblimersen Sodium & Combination Chemotherapy in Treating Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma
  “Manufacturer is no longer making the drug.” (66% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.