Medical College of Wisconsin

Why trials sponsored by Medical College of Wisconsin stopped, in this sample of ClinicalTrials.gov.

20 stopped trials with a clear reason; 85% ended for non-scientific reasons.

Trials

• CPI-613 (Devimistat) in Combination With Chemoradiation in Patients With Pancreatic Adenocarcinoma
  NCT05325281 · TERMINATED · funding or business
  “The pharmaceutical funder pulled funding and no longer plans to develop the drug further.”
• CAR20.19.22 T-cells in Relapsed, Refractory B-cell Malignancies
  NCT05094206 · TERMINATED · regulatory or ethics
  “Treated four patients: 2 at a dose of 1x10\^6 cells/kg and 2 ad at dose of 2.5x10\^6 cells/kg. All four patients had no in-vivo expansion and no meaningful response to therapy. At this point per FDA guidance we will not be treating more patients.”
• Hydroxychloroquine, Abemaciclib and Endocrine Therapy in Hormone Receptor Positive (HR+)/Her 2 Negative Breast Cancer
  NCT04316169 · WITHDRAWN · staffing, sites or logistics
  “Funding and PI leaving institution”
• Point of Care Evaluation of Novir 2019-nCoV Immunoglobulin G/ Immunoglobulin M (IgG/IgM) Antibody Test (Collodial Gold)
  NCT04902911 · TERMINATED · futility
  “Failed to meet FDA criteria on one target at FDA, CDC, and market is not looking for rapid antibody tests.”
• Cardiac Uptake of 18F Florbetapir in Patients Undergoing Chemotherapy
  NCT03333551 · TERMINATED · slow enrollment
  “slow recruitment.”
• Effectiveness of Electrical Neurostimulation in Cyclic Vomiting Syndrome.
  NCT04721171 · TERMINATED · staffing, sites or logistics
  “Halted prematurely Due to COVID-19 and Investigator left institution”
• Solid Tumor Imaging MR-Linac (STIM Study)
  NCT03500081 · SUSPENDED · funding or business
  “Funding”
• Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)
  NCT03150004 · TERMINATED · funding or business
  “No longer have funding support to complete the pharmacogenetics component.”
• Caphosol Study: Prevention of Oral Mucositis in Children, Adolescents and Young Adults Receiving Chemotherapy
  NCT02539342 · TERMINATED · funding or business
  “Lack of funding”
• Novel Testing Procedures
  NCT01793506 · WITHDRAWN · funding or business
  “Never funded or completed”
• Comparative Effectiveness Trial in the Treatment of Pediatric Plaque Morphea
  NCT02680717 · WITHDRAWN · regulatory or ethics
  “Unable to obtain IRB approval at all sites”
• Right-sided Retroflexion With Standard Adult Versus Pediatric Colonoscopes
  NCT01675934 · WITHDRAWN · staffing, sites or logistics
  “PI has left institution”
• Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901)
  NCT01339910 · TERMINATED · other
  “Accrual terminated as recommended by the data and safety monitoring board.”
• Vitamin D Deficiency and Atopic Dermatitis
  NCT01337635 · TERMINATED · slow enrollment
  “Not meeting enrollment goals.”
• Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit
  NCT01050946 · TERMINATED · slow enrollment
  “Only one patient was enrolled. Due to low accrual study was terminated”
• A Composite MR Neuroimaging Marker for Alzheimer's Disease
  NCT01615666 · WITHDRAWN · other
  “This was never a clinical trial and should never have been approved.”
• Quality of Life in Pediatric Transplant Patients
  NCT00678002 · TERMINATED · slow enrollment
  “Poor enrollment”
• Evaluation of Yoga for the Treatment of Pediatric Headaches
  NCT00726843 · TERMINATED · slow enrollment
  “Enrollment proceeded too slowly to conduct study as RCT.”
• The Use of L-Carnitine And CoQ10 Supplements In the Treatment of Cyclic Vomiting Syndrome (CVS)
  NCT00728104 · WITHDRAWN · funding or business
  “No funding”
• Carotid Plaque Regression With Statin Treatment Assessed by High Field Magnetic Resonance Imaging (MRI)
  NCT00388843 · WITHDRAWN · staffing, sites or logistics
  “PI has left institution”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.