Autopsy report · NCT03105479

Comparison of Cadazolid Versus Vancomycin in Children With Clostridium Difficile-associated Diarrhea (CDAD)

“Study suspended in October 2017 and terminated April 17, 2018 after decision to discontinue the study drug development”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year before it stopped.
• 1 participant enrolled.
• Results were posted on the registry 1 year after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2, Phase 3

Sponsor

Actelion

Sponsor type

Industry

Conditions

Clostridium Difficile Infection

Interventions

Cadazolid; Vancomycin capsule; Vancomycin solution

Participants

1

Sites

20

Countries

Belgium, Canada, Czechia, Hungary, Italy, Poland, Romania, Spain, United States

Trials that died the same way

• Panobinostat/Velcade in Multiple Myeloma
  “This study was terminated because the drug company stopped making the study drug” (77% match in meaning)
• SCS Research Study
  “Business temporarily suspended study January 2023 with intent to include additional cohorts in future. For business reasons, study terminated April 2024.” (76% match in meaning)
• Emory Latino Diabetes Education Program
  “Enrollment and study activities were suspended in March 2020 due to the COVID-19 pandemic and re-opening the study was delayed pending additional funding. The study was ultimately terminated in January of 2026 due to lack of funding.” (75% match in meaning)
• Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer
  “The study was terminated because we were not able to obtain the study drug.” (74% match in meaning)
• Inflammation-Induced CNS Glutamate Changes in Depression
  “The study was suspended in March 2020 due to the COVID-19 pandemic and ultimately was terminated as it is not safe to test a potent anti-inflammatory drug with ongoing surges of COVID-19.” (73% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.