Autopsy report · NCT03004443

Inflammation-Induced CNS Glutamate Changes in Depression

“The study was suspended in March 2020 due to the COVID-19 pandemic and ultimately was terminated as it is not safe to test a potent anti-inflammatory drug with ongoing surges of COVID-19.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 months before it started.
• Ran for about 2 years 6 months before it stopped.
• 22 participants enrolled.
• Results were posted on the registry 3 years 6 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Emory University

Sponsor type

University, hospital or other

Conditions

Depression

Interventions

Infliximab; Placebo

Participants

22

Sites

1

Countries

United States

Trials that died the same way

• A Study of Pleiotropic Pioglitazone Effects on the Alcoholic Lung (APPEAL Study)
  “Study was suspended in 2020 due to COVID-19 pandemic as a result of recruitment challenges and the inability to conduct all study procedures (e.g., bronchoscopy) per protocol. In late 2021 the decision was made to not re-open the study.” (85% match in meaning)
• A Study of Efficacy of Benzoyl Peroxide Regimens in Treatment of Unpleasant Foot Odor
  “Due to covid 19 outbreaks, the study are suspended.” (84% match in meaning)
• Emory Latino Diabetes Education Program
  “Enrollment and study activities were suspended in March 2020 due to the COVID-19 pandemic and re-opening the study was delayed pending additional funding. The study was ultimately terminated in January of 2026 due to lack of funding.” (83% match in meaning)
• Effect of Classic Ballet Practice on School Children's Postural Balance
  “The study has been suspended because COVID pandemic.” (83% match in meaning)
• Fecal Microbiota Transplant for Primary CDI
  “The study was terminated after a covid-related suspension and the unavailability of drug.” (82% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.