Autopsy report · NCT02857309

Cardiac Contractility Modulation (CCM) Therapy in Subjects With Medically Refractory Heart Failure

“Slow enrolment.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 years 5 months after it had already started.
• Ran for about 4 years before it stopped.
• 50 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Impulse Dynamics

Sponsor type

Industry

Conditions

Heart Failure

Interventions

OPTIMIZER; Optimal medical therapy

Participants

50

Sites

8

Countries

Austria, Germany, Poland, Sweden

Trials that died the same way

• Impact of Septal Vs Apical Pacing on Right and Left Ventricular Performance
  “Due to slow enrolment” (87% match in meaning)
• Integrative Analysis of Tumor Microenvironment and Optimization of Immunotherapy Duration in NSCL Cancer Patients
  “Enrolment was slowlier than expected.” (84% match in meaning)
• Pharmacokinetics and Safety of Moxifloxacin
  “slow enrolment of patients and new insights” (71% match in meaning)
• Safety and Efficacy Trial to Treat Diastolic Heart Failure Using Ambrisentan
  “Poor enrolment” (71% match in meaning)
• Customized Contrast Media Dose Clinical Trial
  “Slow enrollment.” (70% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.