Autopsy report · NCT02240108

One Year Study of Rifaximin Delayed Release (DR) in Crohn's Disease

“The study was terminated early due to difficulty in enrollment and lack of clinical study drug access.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 2 years 11 months before it stopped.
• 81 participants enrolled.
• Results were posted on the registry 1 year 11 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Bausch Health Americas, Inc.

Sponsor type

Industry

Conditions

Crohn's Disease

Interventions

Rifaximin EIR; Placebo

Participants

81

Sites

78

Countries

United States

Trials that died the same way

• Avelumab (Bavencio) With IL-15 in Subjects With Clear-Cell Renal Carcinoma
  “This study was terminated early due to manufacturer withdrawal of support (study medication) due to lack of enrollment.” (89% match in meaning)
• MIRACLE EF Clinical Study
  “The study was terminated early due to low enrollment.” (87% match in meaning)
• Alvimopan Use in Polytraumatized Patients
  “This study was terminated due to failure to enroll, a low volume of patients met criteria.” (85% match in meaning)
• Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer
  “The study was terminated because we were not able to obtain the study drug.” (85% match in meaning)
• A Study to Assess the Impact of Omalizumab on Exercise Capacity, Physical Activity, and Sleep Quality in Participants With Moderate to Severe Allergic Asthma
  “Due to low enrollment, this study was terminated early.” (85% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.