Autopsy report · NCT02219581

Steroids in Total Knee Arthroplasty

“Terminated after considerable time in suspended state due to inadequate staffing, the COVID pandemic, and the Responsible Party leaving Emory in August 2022.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 1 year 2 months before it stopped.
• 1 participant enrolled.
• Results were posted on the registry 6 years 10 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Thomas L Bradbury

Sponsor type

University, hospital or other

Conditions

Postoperative Pain; Inflammation; Osteoarthritis

Interventions

Dexamethasone 10 mg; Dexamethasone 20 mg; Standard multimodal pain management regimen; Placebo

Participants

1

Sites

1

Countries

United States

Trials that died the same way

• Measurement of the Partial Pressure of Oxygen in Cutaneous Tumors Using Electron Paramagnetic Resonance (EPR) Oximetry
  “Terminated March 22, 2022 due to COVID-19 pandemic” (65% match in meaning)
• Efficacy and Safety of Salkera Emollient Foam in the Treatment of Moderate to Severe Keratosis Pilaris, a Prospective Study
  “terminated due to administrative reasons.” (64% match in meaning)
• Healthy Volunteer Study to Evaluate the Impact of Various Common Interventions on Venous Pressure Signal Captured by PIVA
  “Terminated due to COVID-19” (63% match in meaning)
• Spinal Anesthesia in Total Hip Arthroplasty
  “This study was terminated due to pressing matters related to the COVID-19 pandemic - staff shortages and changes of personnel, data gaps due to the pandemic, participants not being able to continue follow-up visits, and ongoing enrollment issues.” (62% match in meaning)
• Study to Determine the Utility of Wound Vacuum Assisted Closure (VAC) Compared to Conventional Saline Dressing Changes
  “terminated, due to lack enrollment,” (61% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.