Autopsy report · NCT01897714

Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients

“The study was terminated at median 46-48 months long term follow-up and mature overall survival follow-up data.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 6 years 8 months before it stopped.
• 75 participants enrolled.
• Results were posted on the registry 5 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Oncopeptides AB

Sponsor type

Industry

Conditions

Relapsed and/or Relapsed-refractory Multiple Myeloma

Interventions

Melflufen; Dexamethasone

Participants

75

Sites

7

Countries

Denmark, Italy, Netherlands, Sweden, United States

Trials that died the same way

• Prevention of NAFLD in Hispanic Children
  “Study was terminated due to a lack of funding. Data collection was completed for 12-month outcomes; however, funding limitations prevented follow-up for longer timeframes, and some outcomes were not fully collected.” (74% match in meaning)
• PFC Sigma Fixed and Mobile Knee Study
  “The study was terminated at the point the primary endpoint and early milestones were reached and because long term outcomes were available from other sources” (71% match in meaning)
• Study To Determine The Pharmacokinetics Of Sulfasalazine In Children With Juvenile Idiopathic Arthritis
  “Study terminated on 13 April 2016 for business reasons. No safety and/or efficacy concerns contributed to the termination of the study” (69% match in meaning)
• Evaluation of the Clinical and Economic Impact of painPRIMER in the Treatment of Low Back Pain in a Primary Care Setting
  “The study was terminated on 02-Jun-2014 due to slow enrollment. The study was not terminated for reasons of either safety or efficacy.” (69% match in meaning)
• Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid Tumors
  “The study was terminated since there was no need for further safety or efficacy data to be collected. The participants having benefit from the investigational treatments have been moved to a continuation study (NCT05059522)” (69% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.