Autopsy report · NCT01867645

The Impact of IVIG Treatment on Critical Illness Polyneuropathy and/or Myopathy in Patients With MOF and SIRS/Sepsis

“The trial was terminated early due to futility in reaching the primary endpoint.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 8 years 5 months after it had already started.
• Ran for about 6 years 4 months before it stopped.
• 38 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

Medical University of Vienna

Sponsor type

University, hospital or other

Conditions

Polyneuropathies

Interventions

IgM-enriched Intravenous Immunoglobulins; Human Albumin

Participants

38

Sites

1

Countries

Austria

Trials that died the same way

• An Efficacy and Safety Study of Lanabecestat (LY3314814) in Early Alzheimer's Disease
  “An independent assessment concluded the trial was not likely to meet the primary endpoint upon completion and therefore, trial stopped for futility” (83% match in meaning)
• Daratumumab, Ixazomib, Pomalidomide, and Dexamethasone as Salvage Therapy in Relapsed/Refractory Multiple Myeloma
  “The trial met its primary endpoint.” (80% match in meaning)
• Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia
  “Trial failed to meet primary endpoint.” (80% match in meaning)
• Efficacy and Safety of MK-7622 as Adjunct Therapy in Participants With Alzheimer's Disease (MK-7622-012)
  “Stage 1 interim analysis of efficacy met the criteria for early trial termination (futility). The trial was terminated at Stage 1; did not proceed to Stage 2.” (76% match in meaning)
• Merotocin in Mothers With Inadequate Milk Production and Infants Delivered Prematurely
  “The trial was prematurely terminated. Termination was not because of safety concerns but due to slow recruitment.” (76% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.