Autopsy report · NCT01856439

Long Term Safety and Efficacy Study of ProSavin in Parkinson's Disease

“As a result of termination of development of Prosavin, it is no longer possible for Sio to either commence or to continue any related clinical trials.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 years after it had already started.
• Ran for about 10 years 11 months before it stopped.
• 15 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Axovant Sciences Ltd.

Sponsor type

Industry

Conditions

Parkinson's Disease

Interventions

ProSavin

Participants

15

Sites

2

Countries

France, United Kingdom

Trials that died the same way

• Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers
  “The study was terminated due to the sponsor's decision to discontinue the clinical trial.” (58% match in meaning)
• A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes
  “Trial terminated because of lack of efficacy in the short term acute phase.” (58% match in meaning)
• Exploratory Study of Farletuzumab to Treat Resectable, Non-functioning Pituitary Adenomas
  “Trial terminated due to focus of primary therapeutic areas.” (57% match in meaning)
• --SuPERIOR Trial--
  “Study Terminated Prior to trial activation, due to changes in SOC of the treatment” (57% match in meaning)
• A Dose Range Finding Study of JNJ-38518168 in Patients With Active Rheumatoid Arthritis in Spite of Treatment With Methotrexate
  “The decision was made to prematurely discontinue this trial due to lack of efficacy.” (56% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.