Autopsy report · NCT01763684

Oxford Signature vs. Conventional Global Study

“Due to slow enrollment and not being able to reach the primary endpoint”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months after it had already started.
• Ran for about 3 years 11 months before it stopped.
• 266 participants enrolled.
• Results were posted on the registry 4 years 8 months after it ended.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Zimmer Biomet

Sponsor type

Industry

Conditions

Osteoarthritis; Osteoarthritis, Knee; Osteonecrosis

Interventions

Signature Custom Guides; Conventional Instrumentation

Participants

266

Sites

7

Countries

United States

Trials that died the same way

• Stereotactic Body Radiation Therapy in Treating Patients With Metastatic or Recurrent Kidney Cancer
  “due to slow enrollment” (80% match in meaning)
• Proton Radiation Therapy for Pituitary Adenoma
  “Due to slow enrollment and feasibility issues.” (78% match in meaning)
• EXCimEr Laser for Long lENgTh Lesions in Below-The-Knee Arteries Study
  “too slow enrollment” (74% match in meaning)
• A Feasibility Study on Ultrafiltration and Blood Volume Measurements
  “Slow enrollment” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.