Autopsy report · NCT01628874

Jet Injection of 1% Buffered Lidocaine Versus Topical EMLA for Local Anesthesia Before Lumbar Puncture in Children

“Due to low recruitment numbers, the study was terminated.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 3 years 11 months before it stopped.
• 66 participants enrolled.
• Results were posted on the registry 2 years 10 months after it ended.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

University of Colorado, Denver

Sponsor type

University, hospital or other

Conditions

Lumbar Puncture; Topical Analgesia

Interventions

J-Tip; EMLA; Lidocaine

Participants

66

Sites

1

Countries

United States

Trials that died the same way

• To Determine the Objective Response Rate of 4 Cycles of Docetaxel + Anthracycline (Epirubicin or Doxorubicine) Followed by 4 Cycles of Docetaxel Single Agent
  “the study was early terminated due to lack of recruitment.” (92% match in meaning)
• Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery
  “The study was terminated due to a considerably lower recruitment rate than anticipated” (91% match in meaning)
• Safety, Tolerability and Efficacy of AVP-786 for the Treatment of Disinhibition
  “The study was terminated prematurely because of difficulty with recruiting.” (88% match in meaning)
• Enhancing Anti--Tetanus Vaccine Response After Autologous Stem Cell Transplantation
  “Study terminated prematurely due to poor recruitment.” (88% match in meaning)
• Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome
  “The study was terminated due to recruitment challenges” (88% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.