Autopsy report · NCT01581255

The Effect of High Frequency Oscillation on Biological Markers of Lung Injury

“Parent study (OSCILLATE) stopped by the Data Monitoring Committee”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months after it had already started.
• Ran for about 6 months before it stopped.
• 2 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Sponsor

Canadian Critical Care Trials Group

Sponsor type

University, hospital or other

Conditions

Acute Respiratory Distress Syndrome

Participants

2

Sites

2

Countries

Canada

Trials that died the same way

• A Study of Ponsegromab in People With Heart Failure
  “Following a prespecified interim analysis, and in consultation with the independent Data Monitoring Committee, the Sponsor terminated the study” (58% match in meaning)
• Hirschsprung Disease Trends in the United States: Analysis of the National Inpatient Sample
  “Per PI, the study was terminated prematurely since the data collection was completed” (57% match in meaning)
• The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM
  “Independent Data Monitoring Committee recommendation to stop due to futility” (56% match in meaning)
• Azithromycin for Severe Acute Malnutrition in CMAM, Nigeria
  “Study was halted due to low follow-up rates and issues with data collection” (56% match in meaning)
• To Assess The Efficacy and Safety Of Oral Sildenafil in the Treatment of Pulmonary Arterial Hypertension.
  “This study was terminated at the recommendation of an independent Data Monitoring Committee. The decision was not based on any safety concerns.” (56% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.