Autopsy report · NCT01404767

Tight Hemodynamic Control in Patients Who Are Chronically on Metoprolol

“Enrollment slow over 2 years a change in the population less on metoprolol than initially anticipated”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months after it had already started.
• Ran for about 2 years 8 months before it stopped.
• 20 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

University Health Network, Toronto

Sponsor type

University, hospital or other

Conditions

Vascular Disease; Hypertension; Angina; Cardiac Disease

Interventions

Esmolol; Metoprolol

Participants

20

Sites

1

Countries

Canada

Trials that died the same way

• Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer
  “Lack of efficacy in Cohort 2; slow enrollment in Cohort 1” (62% match in meaning)
• Use of 3M Cavilon Advanced Skin Protectant in the Management of Damaged Skin Around an Ostomy, Drain or Fistula
  “Slow enrollment of patients” (62% match in meaning)
• Lumbar Disc Herniation Outcome Measures
  “Slow/low enrollment” (62% match in meaning)
• Zileuton CR vs Placebo in Poorly Controlled Asthma Patients on Moderate Dose ICS
  “Slower than anticipated enrollment” (62% match in meaning)
• Observational Study of CT Dye Administration Through the Intraosseous Vascular Access Route
  “Slow rate of enrollment” (61% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.