Autopsy report · NCT01367210

Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA)

“Because a higher rate of virological failures in study versus control arm.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 4 years before it stopped.
• 165 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Catholic University of the Sacred Heart

Sponsor type

University, hospital or other

Conditions

HIV Infection

Interventions

Maraviroc, Darunavir/r; current antiretroviral therapy with 3 drugs

Participants

165

Sites

1

Countries

Italy

Trials that died the same way

• Pre-therapeutic Identification of Dihydropyrimidine Dehydrogenase Gene (DPD) Deficiency for Predicting Toxicity to Fluoropyrimidines
  “The study stopped due to a death in the arm control” (61% match in meaning)
• Treatment for Alcohol Dependence With Gabapentin
  “Due to poor compliance of patients in the study.” (56% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.