Autopsy report · NCT01232556

A Study Of Inotuzumab Ozogamicin Plus Rituximab For Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma Patients Who Are Not Candidates For Intensive High-Dose Chemotherapy

“The study was terminated prematurely on May 16, 2013, for futility. No new or unexpected safety issues were identified.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 months before it started.
• Ran for about 3 years before it stopped.
• 338 participants enrolled.
• Results were posted on the registry 4 years 5 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Pfizer

Sponsor type

Industry

Conditions

Lymphoma, Non-Hodgkin

Interventions

Inotuzumab ozogamicin; Rituximab; rituximab + gemcitabine; rituximab +bendamustine

Participants

338

Sites

177

Countries

Belgium, Bulgaria, Canada, Croatia, Czechia, France, Germany, Hungary, India, Ireland, Japan, Lithuania and more

Trials that died the same way

• Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults
  “This study was terminated early due to futility.” (86% match in meaning)
• An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida
  “The study was terminated prematurely on May 18, 2012 due to slow enrollment. The study was not terminated due to any safety issues or concerns.” (80% match in meaning)
• Study To Determine The Pharmacokinetics Of Sulfasalazine In Children With Juvenile Idiopathic Arthritis
  “Study terminated on 13 April 2016 for business reasons. No safety and/or efficacy concerns contributed to the termination of the study” (80% match in meaning)
• Trial to Evaluate UltraSound in the Treatment of Tibial Fractures
  “Study was terminated due to futility” (80% match in meaning)
• Study of Nintedanib and Chemotherapy for Advanced Pancreatic Cancer
  “The study was terminated due to futility and lack of future funding” (80% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.