Autopsy report · NCT01181921

The CIRCADIAN Study: Evaluation of Modulating Effect of Galantamine on Circadian Rhythm in Patients With Mild to Moderate Alzheimer's Disease

“The recruitment rate was very low (one screening failure and one early withdrawal patient)”

The sponsor’s own words in the registry.

Life of this trial

• Registered 9 months before it started.
• Ran for about 1 month before it stopped.
• 1 participant enrolled.
• Results were posted on the registry 1 year 2 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Janssen-Cilag, S.A.

Sponsor type

Industry

Conditions

Alzheimer Disease

Interventions

Galantamine

Participants

1

Sites

1

Countries

Spain

Trials that died the same way

• Comparing Satisfaction With a Participatory Driven Web-application and a Standard Website
  “The primary trial was stopped. Since, a feasibility study showed that recruitment was not feasible. We obtain a recruitment rate of 15 %.” (76% match in meaning)
• The Effect of Ovamax on Oocyte Quality
  “The study was stopped prematurely due to low recruitment rate” (76% match in meaning)
• A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Lamivudine Resistant HBeAg-Negative Chronic Hepatitis B.
  “Low recruitment rate due to treatment regimen change” (75% match in meaning)
• Safety and Efficacy of Maraviroc and/or Favipiravir With Standard Therapy in Severe COVID-19 Adults
  “No more patients complying the selection criteria were available for recruitment” (74% match in meaning)
• Effects (Long Term Analysis) of an Hyperproteinic Nutrition on Neonates With Intra-uterine Growth Delay : a Prospective, Multicentric , Randomized, Double Blind Study ("Proneonat")
  “difficulties of recruitment, high number of patients lost to follow-up” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.