Autopsy report · NCT01076699

A Four Arm Study to Evaluate the Safety and Efficacy of 3 Different Doses of RVX-100 Versus Placebo in Subjects With Irritable Bowel Syndrome Accompanied by Diarrhea (IBS-D)

“recruiting/enrolling participants has halted prematurely but potentially will resume Oct”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Suspended: paused, and may or may not restart.
• 192 participants planned (an estimate, not an actual count).

Vital statistics

Status

Suspended

Phase

Phase 2

Sponsor

Revogenex, Inc.

Sponsor type

Industry

Conditions

Irritable Bowel Syndrome

Interventions

0.075 mg RVX-100; 0.125 mg RVX-100; 0.250 mg RVX-100; placebo

Participants

192 (planned, not actual)

Sites

1

Countries

United States

Trials that died the same way

• Ultrasound and Endometrial Hyperplasia
  “enrollment of participants has halted prematurely; difficulty with recruitment” (85% match in meaning)
• Platelet Reactivity With Fentanyl, Morphine, or no Narcotic
  “The study was halted prematurely due to difficulties in recruiting a sufficient number of participants. Despite efforts to enroll eligible individuals, the recruitment goals were not met, making it infeasible to continue the study as planned.” (70% match in meaning)
• High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery
  “Study halted prematurely, prior to enrollment of first patient, due to recruiting problems.” (69% match in meaning)
• Efficacy and Safety Study of 4975 in Patients Undergoing Total Hip Replacement
  “Enrollment of patients has halted prematurely and will not resume. No future patients will be enrolled or treated.” (69% match in meaning)
• BELIEVE Study: Nesiritide and Post Myocardial Infarction Left Ventricular Modeling
  “recruitment of subjects was halted prematurely. recruiting subjects halted prematurely” (69% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.