Autopsy report · NCT00683267

Efficacy and Safety Study of 4975 in Patients Undergoing Total Hip Replacement

“Enrollment of patients has halted prematurely and will not resume. No future patients will be enrolled or treated.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 8 months after it had already started.
• Ran for about 1 year 3 months before it stopped.
• 118 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Anesiva, Inc.

Sponsor type

Industry

Conditions

Arthroplasty

Interventions

4975, highly purified capsaicin; Placebo

Participants

118

Sites

10

Countries

United States

Trials that died the same way

• Myfortic or CellCept Gastrointestinal Effects in African American Kidney Recipients
  “enrollment halted in order to have all patients complete follow-up by Jan 2011” (78% match in meaning)
• High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery
  “Study halted prematurely, prior to enrollment of first patient, due to recruiting problems.” (76% match in meaning)
• Comparison of Efficacy of Behavioral Approaches for Treatment of Insomnia
  “Study halted prematurely and will not resume; participants are no longer being examined or receiving intervention. COVID Complications.” (75% match in meaning)
• Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy
  “The study was prematurely halted primarily due to low patient accrual. Despite efforts to optimize recruitment, the enrollment rate remained insufficient to meet the predefined targets, and continuation was deemed unfeasible” (74% match in meaning)
• RECELL to Promote Healing Following Carbon Dioxide (CO2) Laser Treatment in Cosmetic Patients
  “Study halted prematurely and will not resume; participants are no longer being examined or receiving intervention. PI decided to terminate due to slow enrollment.” (71% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.