Autopsy report · NCT00958633

Mood Stabilizer (MS)+ Antidepressant vs MS + Placebo in Maintenance of Bipolar Disorder.

“Recruitment was stopped before the planned sample size was reached owing to the Covid-19 pandemic and expiration of funding.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 year 3 months before it started.
• Ran for about 9 years 6 months before it stopped.
• 237 participants enrolled.
• Results were posted on the registry 5 years after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

University of British Columbia

Sponsor type

University, hospital or other

Conditions

Bipolar I Disorder

Interventions

Escitalopram; Bupropion XL

Participants

237

Sites

1

Countries

Canada

Trials that died the same way

• Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes
  “Slow recruitment due to COVID-19, the study was stopped when recruited numbers fulfilled the pre-defined lower sample size.” (86% match in meaning)
• A First-in-Human Study of ALK-N001 for Injection in Patients With Advanced Solid Tumors
  “Participant recruitment has been stopped because the planned sample size has been reached.” (79% match in meaning)
• Evaluating a Novel Web-based Intervention for Breast Cancer Survivors
  “Participant recruitment was stopped due to corona pandemic.” (78% match in meaning)
• Evaluation of Skin Cleansers and Skin Protectants in Management of Incontinence-associated Dermatitis
  “Early termination due to COVID-19 pandemic led to inability to reach planned sample size” (76% match in meaning)
• Diet and Exercise Frailty Intervention in Cardiac Device Patients
  “Due to COVID-19 Pandemic Recruitment was not started” (76% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.