Autopsy report · NCT00403780

Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia

“low inclusion rate”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 months after it had already started.
• Ran for about 9 years 1 month before it stopped.
• 18 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Karolinska Institutet

Sponsor type

University, hospital or other

Conditions

Critical Limb Ischemia; Arterial Occlusive Disease; Pain; Ischemia

Interventions

pregabalin; placebo

Participants

18

Sites

3

Countries

Sweden

Trials that died the same way

• Risk of Rupture of Aneurysms of the Thoracic Ascending Aorta (ATA) From the Dynamic Imaging
  “low inclusion rates” (97% match in meaning)
• PET / CT With 18F-FDG: Does it Optimize the I 123-MIBG Imaging Results in the Search for Discriminating Factors for the Implementation of an Implantable Defibrillator?
  “Inclusion rate too slow / infeasible.” (86% match in meaning)
• Video-Assisted Thoracoscopic Pulmonary Vein Isolation Versus Percutaneous Catheter Ablation in Atrial Fibrillation Trial
  “Inclusion rate insufficient” (86% match in meaning)
• Respiratory Variations for Assessing Blood Withdrawal 2
  “insufficient inclusion rate” (85% match in meaning)
• Dexmedetomidine Pharmacokinetics-pharmacodynamics in Mechanically Ventilated Children With Single-organ Respiratory Failure
  “Poor inclusion rate.” (85% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.