Autopsy report · NCT00355251

Influence of Atorvastatin on Viral Replication During Antiretroviral Treatment Interruption

“On the basis of published results of SMART study, it has been observed that the results are worse in patients who have interrupted their treatments.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 7 months before it stopped.
• 5 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Germans Trias i Pujol Hospital

Sponsor type

University, hospital or other

Conditions

HIV Infections

Interventions

Atorvastatin 40 mg/Atorvastatin 80 mg

Participants

5

Sites

1

Countries

Spain

Trials that died the same way

• Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies
  “The study was interrupted early and terminated when only 26 out of 80 patients were enrolled due to new clinical study results indicating that the current study would not be informative.” (72% match in meaning)
• Inotropic Treatment With Levosimendan (SimdaxR)in Heart Surgery
  “The study was stopped due to difficulties in including patients” (66% match in meaning)
• Utility of Tocolytic Therapy for Maintenance Tocolysis in the Management of Threatened Preterm Delivery
  “have been published new studies that it showed the ineffectiveness of the treatments proposed in this study.” (66% match in meaning)
• Irreversible Electroporation + Nivolumab for Patients With Metastatic Pancreatic Cancer
  “The study was terminated on the basis on an evaluation of the safety and efficacy of the 9 included patients of which 2 of the patients were excluded before receiving any study treatments, thus 7 patients were treated in the study.” (64% match in meaning)
• Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid Tumors
  “The study was terminated since there was no need for further safety or efficacy data to be collected. The participants having benefit from the investigational treatments have been moved to a continuation study (NCT05059522)” (63% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.