Autopsy report · NCT00089856

GVAX® Vaccine for Prostate Cancer vs Docetaxel & Prednisone in Patients With Metastatic Hormone-Refractory Prostate Cancer

“Based on futility analysis showing \<30% chance of meeting primary endpoint.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month after it had already started.
• Ran for about 4 years 3 months before it stopped.
• 626 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Cell Genesys

Sponsor type

Industry

Conditions

Prostate Cancer

Interventions

Immunotherapy with allogeneic prostate vaccine; Chemotherapy (Taxotere and prednisone)

Participants

626

Sites

126

Countries

Belgium, Canada, France, Germany, Netherlands, Sweden, United Kingdom, United States

Trials that died the same way

• Evaluation of Effectiveness of ALBENDAZOLIVERMECTIN Coformulation vs ALBENDAZOLE for Treatment of Intestinal Worms
  “Primary Endpoint met” (68% match in meaning)
• CTLA-4 Blockade and Low Dose Cyclophosphamide in Patients With Advanced Malignant Melanoma
  “Primary Endpoint not met” (60% match in meaning)
• Utilization of Autologous Mesenchymal Cells in Posterolateral Spinal Fusion in Degenerative Spine Disease
  “Primary endpoint (Safety) has been achieved” (59% match in meaning)
• A Study of Avastin (Bevacizumab) in Combination With Platinum-Based Chemotherapy in Patients With Advanced or Recurrent Squamous Non-Small Cell Lung Cancer
  “Primary (safety) endpoint reached” (59% match in meaning)
• Ipilimumab, Nivolumab, Tocilizumab and Radiation in Pretreated Patients With Advanced Pancreatic Cancer
  “primary endpoint was not met” (58% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.