Autopsy report · NCT06411132

Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry Eye

“The analyses presented are based on a database lock date of 05 March 2025.The study was prematurely interrupted by Dompé following a review of the database, which determined that an acceptable no. of patients was reached to meet the trial objectives.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 8 months before it stopped.
• 103 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Sponsor

Dompé Farmaceutici S.p.A

Sponsor type

Industry

Conditions

Sjögren Syndrome; Dry Eye

Interventions

observational study

Participants

103

Sites

15

Countries

United States

Trials that died the same way

• Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies
  “The study was interrupted early and terminated when only 26 out of 80 patients were enrolled due to new clinical study results indicating that the current study would not be informative.” (66% match in meaning)
• AZD1222 Vaccine for the Prevention of COVID-19
  “The study was put on hold in September 2020 due to a safety concern in another trial but never restarted. In the meantime our clinical development program now includes a similar study with a different design, which we prefer to complete now.” (64% match in meaning)
• A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA)
  “The study was closed by the Sponsor according to the protocol-specified minimum post-treatment follow-up period of 3 years.” (64% match in meaning)
• Inotropic Treatment With Levosimendan (SimdaxR)in Heart Surgery
  “The study was stopped due to difficulties in including patients” (63% match in meaning)
• Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease
  “Study has been suspended due to clinical hold.” (62% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.