Autopsy report · NCT06041919

Evaluating the Early Bactericidal Activity, Safety and Tolerability of Nebulised RESP301 in Adults With Tuberculosis

“Decision was made by the sponsor not to progress to Stage 2”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 1 year 5 months before it stopped.
• 20 participants enrolled.
• Results were posted on the registry 4 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Thirty Respiratory Limited

Sponsor type

Industry

Conditions

Rifampicin Susceptible Pulmonary Tuberculosis

Interventions

RESP301; HRZE

Participants

20

Sites

1

Countries

South Africa

Trials that died the same way

• A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors
  “Following completion of Phase 1b, the Sponsor decided not to initiate Part 2 of the trial.” (73% match in meaning)
• A Dose-escalation and Safety & Efficacy Study of AXO-AAV-GM2 in Tay-Sachs or Sandhoff Disease
  “Sponsor withdrew from the study and there was a lack of funding to complete stage 2 of the designed study.” (71% match in meaning)
• Yttrium-90 Radioembolization + Nivolumab for Liver + Extra-hepatic Metastases From Colorectal Cancer
  “Sponsor chose not to continue” (70% match in meaning)
• SURF, Neurodevelopment, Growth Study in SGA Infants
  “Sponsor decision stopped in June 2017” (67% match in meaning)
• A Multicentre, Open Label, Phase 1 Trial in Japan of the Mitogen Activated Protein Extracellular Signal Regulated Kinase (MEK) Inhibitor Pimasertib Given Orally to Subjects With Solid Tumors as Monotherapy
  “The sponsor decided not to conduct the expansion part of trial (part 2)” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.