Autopsy report · NCT05921695

The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke

“Terminated due to protocol amendment: intervention window changed from entire ED stay to first 2h after ED admission. Revised protocol will be registered separately.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 3 years before it stopped.
• 104 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Second Affiliated Hospital, Zhejiang University, School of Medicine

Sponsor type

University, hospital or other

Conditions

Heat Stroke

Interventions

Normal Saline infusion and Ringer lactate infusion

Participants

104

Sites

7

Countries

China

Trials that died the same way

• A Clinical Trial to Study Single- and Multiple- Doses of GSM-779690T in Healthy Participants
  “The protocol is being withdrawn prior to enrollment due to a redesign of the study approach under the existing IND.” (62% match in meaning)
• Study of Inborn Errors of Cholesterol Synthesis and Related Disorders
  “Study terminated due to low enrollment and availability of alternative protocols.” (59% match in meaning)
• Clinical Data Collection for Obstetric Ultrasound Algorithms
  “Study paused temporarily pending IRB approval of an amendment to the protocol and consent form.” (57% match in meaning)
• Integrative Liver-Targeted Therapy for Diabetic Macular Edema: Using "Tauroursodeoxycholate" or Traditional Chinese Medicine.
  “The study was terminated due to additional regulatory requirements that could not be completed within the established academic timeline. As a result, continuation of the study was not feasible.” (56% match in meaning)
• Pemetrexed and Cisplatin as Treatment in Small Cell Lung Cancer
  “Terminated due to lack of efficacy” (56% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.