Autopsy report · NCT05349721

Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS

“Company decision”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 2 years 8 months before it stopped.
• 336 participants enrolled.
• Results were posted on the registry 6 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

PTC Therapeutics

Sponsor type

Industry

Conditions

Amyotrophic Lateral Sclerosis

Interventions

PTC857; Placebo

Participants

336

Sites

55

Countries

Argentina, Australia, Belgium, Czechia, France, Germany, Italy, Japan, Netherlands, Poland, Spain, Sweden and more

Trials that died the same way

• 3D011-08 Monotherapy in Subjects With Advanced Solid Tumors
  “Company's decision” (97% match in meaning)
• V-Chordal Adjustable System for Chordal Replacement in Mitral Valve Insufficiency Due to Leaflet Prolapse
  “Company business decision” (92% match in meaning)
• A Dose Escalation/Expansion Study of MDK-703 in Patients With Advanced or Metastatic Solid Tumors
  “Corporate decision” (90% match in meaning)
• HDM201 in Combination With MBG453 or Venetoclax in Patients With Acute Myeloid Leukemia (AML) or High-risk Myelodysplastic Syndrome (MDS)
  “Business decision” (83% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.