Autopsy report · NCT05225532

Cardioneuroablation: Comparison of Right Versus Left Atrial Approach in Patients With Reflex Syncope

“Significant differences between the groups were noted during interim analysis (as scheduled in the protocol) and the study was stopped because the final result was obtained”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 11 months before it stopped.
• 40 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Centre of Postgraduate Medical Education

Sponsor type

University, hospital or other

Conditions

Reflex Syncope

Interventions

Radiofrequency ablation

Participants

40

Sites

1

Countries

Poland

Trials that died the same way

• Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer
  “Per protocol, the study was terminated based on interim analysis results” (81% match in meaning)
• Do Peanut Shaped Birthing Balls Reduce the Length of Labor in Patients With Epidural Analgesia?
  “During interim analysis, it appeared there were no difference in groups” (74% match in meaning)
• LBH589 in Refractory Myelodysplastic Syndromes (MDS)
  “Per protocol, the results of a planned interim analysis demonstrated insufficient efficacy and led to early termination of the study.” (73% match in meaning)
• Study of Pemetrexed for Second-Line Pancreas Cancer
  “At interim analysis the study did not meet the response criteria to continue” (72% match in meaning)
• Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics
  “study paused for interim analysis” (71% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.