Autopsy report · NCT05168475

Biologics in Refractory Vasculitis: A Trial of Biologic Therapy for Refractory Primary Non-ANCA Associated Vasculitis

“NIHR withdrawal of funding”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 months after it had already started.
• Ran for about 2 years 4 months before it stopped.
• 22 participants enrolled.
• Results were posted on the registry 1 year 7 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Cambridge University Hospitals NHS Foundation Trust

Sponsor type

University, hospital or other

Conditions

Giant Cell Arteritis; Takayasu Arteritis; Cogan Syndrome; Relapsing Polychondritis; Cryoglobulinemic Vasculitis; IgA Vasculitis

Interventions

Rituximab; Infliximab; Tocilizumab

Participants

22

Sites

5

Countries

United Kingdom

Trials that died the same way

• Vaccination of Patients With Ovarian Cancer With Dendritic Cell/Tumor Fusions With Granulocyte Macrophage Colony-stimulating Factor (GM-CSF) and Imiquimod
  “Withdrawal of funding” (72% match in meaning)
• Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
  “Funding withdrawal” (72% match in meaning)
• Developing a Childhood Asthma Risk Passive Digital Marker
  “NIH funding was terminated due to new agency priorities.” (71% match in meaning)
• Docetaxel and Capecitabine in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cavity Cancer
  “funding withdrawn” (67% match in meaning)
• Comparison of Trelstar Versus Lupron or Zoladex in Advanced Prostate Cancer
  “Withdrawal of funding support” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.