Autopsy report · NCT05167370

High Dose Chemotherapy With Amifostine and Autologous Stem Cell Transplantation for High Risk Relapsed Pediatric Solid Tumors and Brain Tumors

“The study was terminated as recommended by the DSMB due to inability to meet enrollment goals within the time frame allotted (target of 25 patients over 5 years).”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 year 8 months after it had already started.
• Ran for about 1 year 4 months before it stopped.
• 2 participants enrolled.
• Results were posted on the registry 9 years 9 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Children's Hospital Medical Center, Cincinnati

Sponsor type

University, hospital or other

Conditions

Solid Tumors; Brain Tumors

Interventions

Amifostine

Participants

2

Sites

1

Countries

United States

Trials that died the same way

• HepaSphere/Quadrasphere Microspheres for Delivery of Doxorubicin for the Treatment of Hepatocellular Cancer
  “The clinical study was terminated due to the inability to meet target enrollment.” (77% match in meaning)
• Alvimopan Use in Polytraumatized Patients
  “This study was terminated due to failure to enroll, a low volume of patients met criteria.” (77% match in meaning)
• Evaluation of the Clinical and Economic Impact of painPRIMER in the Treatment of Low Back Pain in a Primary Care Setting
  “The study was terminated on 02-Jun-2014 due to slow enrollment. The study was not terminated for reasons of either safety or efficacy.” (77% match in meaning)
• Phase 2 Study of OBP-301 (Telomelysin™) in Combination With Pembrolizumab and SBRT in Patients With HNSCC With Inoperable, Recurrent or Progressive Disease
  “This study was terminated due to low participant enrollment.” (74% match in meaning)
• The Effect on Mucosal Healing With Pentasa Sachet in Mild to Moderate Active "Drug: Crohn's Disease"
  “Study terminated due to lack of eligible patients” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.