Autopsy report · NCT05091528

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

“Sponsor decision based on strategic re-alignment”

The sponsor’s own words in the registry.

Life of this trial

• Registered 4 months before it started.
• Ran for about 5 months before it stopped.
• 2 participants enrolled.
• Results were posted on the registry 1 month after it ended.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Silverback Therapeutics

Sponsor type

Industry

Conditions

HER2-positive Breast Cancer; HER2-positive Gastric Cancer; HER2-positive Colorectal Cancer; HER2-expressing Non-small Cell Lung Cancer

Interventions

SBT6050; trastuzumab deruxtecan; tucatinib; trastuzumab; capecitabine; trastuzumab deruxtecan

Participants

2

Sites

1

Countries

United States

Trials that died the same way

• 99mTc-rhAnnexin V-128 Imaging for Carotid Atherosclerosis
  “Sponsor Decision based on strategic considerations” (85% match in meaning)
• Study of ALVR106 in Patients With Respiratory Viral Infections After Hematopoietic Cell and Solid Organ Transplant
  “Strategic sponsor decision” (84% match in meaning)
• Pitolisant (BF2.649) in the Treatment of Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnoea Syndrome, Treated or Not by Nasal Continuous Positive Airway Pressure, But Still Complaining of Excessive Daytime Sleepiness
  “Strategic decision of Sponsor” (84% match in meaning)
• Study of Efficacy, Safety, and Tolerability of LYS006, in Patients With Mild to Moderate Ulcerative Colitis
  “Sponsor decision due to strategic considerations” (83% match in meaning)
• Efficacy and Safety of Nitazoxanide for Post Exposure Prophylaxis of COVID-19
  “Sponsor's strategic decision” (82% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.