Autopsy report · NCT04981678

The Effect of Buprenorphine Continuation for Patients With Opioid Use Disorder

“This study was halted prior to accumulating the full number of participants due to difficulty in recruiting study subjects.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 6 months before it started.
• Ran for about 1 year 9 months before it stopped.
• 12 participants enrolled.
• Results were posted on the registry 1 year 2 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

MaineHealth

Sponsor type

University, hospital or other

Conditions

Opioid-use Disorder

Interventions

Buprenorphine; Buprenorphine

Participants

12

Sites

1

Countries

United States

Trials that died the same way

• Platelet Reactivity With Fentanyl, Morphine, or no Narcotic
  “The study was halted prematurely due to difficulties in recruiting a sufficient number of participants. Despite efforts to enroll eligible individuals, the recruitment goals were not met, making it infeasible to continue the study as planned.” (82% match in meaning)
• High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery
  “Study halted prematurely, prior to enrollment of first patient, due to recruiting problems.” (77% match in meaning)
• Nifedipine or Nifedipine Plus Indomethacin for Treatment of Acute Preterm Labor
  “Study halted due to slow recruitment” (77% match in meaning)
• Exercise to Prevent Aromatase Inhibitor Side Effects in Breast Cancer Patients
  “The study was stopped due to recruitment difficulties” (77% match in meaning)
• Trial to Evaluate the Efficacy and Safety of Nitazoxanide (NTZ) for Post-Exposure Prophylaxis of COVID-19 and Other Viral Respiratory Illnesses in Elderly Residents of Long-Term Care Facilities (LTCF)
  “Study recruitment was halted prematurely as widespread vaccination of the study population made completion infeasible.” (76% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.